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Correlation between lymphocyte/monocyte ratio and skin pruritus in elderly hemodialysis patients

【来源:《华夏医学》编辑部 | 作者:QIN Xinfang,etc. | 编辑:李佳睿 | 发布日期:2024-09-18】

QIN Xinfang, ZOU Disha, LI Kanghui, WANG Ying, LI Zhaorong

( Department of Neonatology, Affiliated Hospital of Guilin Medical 

University, Guilin 541001, China)

Abstract Objective To explore the correlation between lymphocyte/monocyte ratio ( LMR) and pruritus in elderly patients with maintenance hemodialysis ( MHD ) . Methods The clinical data of 74 elderly patients with MHD were collected, and LMR was calculated. According to the Chinese 14-Item UP-Dial Scale questionnaire, the patients were divided into no, mild, moderate and severe pruritus groups. The clinical data of different pruritus groups were compared, and the influencing factors of pruritus patients were analyzed by Logistic regression model. Results The itch score of elderly patients with diabetic nephropathy was significantly higher than that in other primary disease group. There was no statistical difference in the level of LMR among all groups with primary disease ( P > 0. 05 ) . The fasting blood glucose, glycated hemoglobin, urea reduction rate ( URR) , direct bilirubin and LMR of elderly patients between the no-itch group and each itch groups were compared. The differences were statistically significant ( P< 0. 05) , and multiple Logistic regression analysis showed that LMR was an independent protective factor for pruritus ( P<0.05) . Conclusion LMR is associated with pruritus in elderly with patients.

Keywords: lymphocytes/monocytes; maintenance hemodialysis; skin pruritus

DOI:10.19296/j.cnki.1008-2409.2024-03-010

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