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LI Xiaona^a, HOU Shuaihui^b, WANG Caili^a

( a. Department of Traditional Chinese Medicine, b. Department of 

Respiratory,Yanshi People¡äs Hospital, Yanshi 471900, China)

Abstract Objective To explore the effects of Qingfei-Yangyin decoction combined with non-invasive ventilation on chronic obstructive pulmonary disease ( COPD) and its influence on lung compliance and oxygenation function. Methods 130 patients with COPD in Yanshi People¡äs Hospital from June 2021 to June 2023 were selected and randomly divided into observation group ( n = 65) and control group ( n = 65) . The control group was treated with non-invasive ventilation, and the observation group was treated with Qingfei-Yangyin decoction combined with non-invasive ventilation. Both groups were treated for two weeks. The therapeutic effects of two groups, including TCM syndrome score, forced expiratory volume in the first second ( FEV1 ) , maximal expiratory flow ( MEF ) , percentage of FEV1 in predicted value ( FEV1 % pred) , fored vital capacity ( FVC) , oxygenation index ( PaO2/FiO2 ) , arterial partial pressure of carbon dioxide ( PaCO2) , arterial partial pressure of oxygen ( PaO2) and lung compliance were analyzed. Results The total effective rate of the observation group treatment was 95.38% in the observation group, which was higher than 83.08% in the control group ( P< 0.05) . Compared with the control group, the TCM syndrome score of the observation group was lower after 2 weeks of treatment ( P< 0.05) . After 2 weeks of treatment, FVC, MEF, FEV1 %pred and FEV1 in the observation group were higher than those in the control group ( P< 0.05) PaO2 and PaO2/FiO2 in the observation group were higher, and PaCO2 and lung compliance were lower ( P< 0. 05) . Conclusion Qingfei-Yangyin decoction combined with non-invasive ventilation in the treatment of COPD patients can significantly enhance the curative effect, improve lung function, lung compliance and oxygenation function, and reduce clinical symptoms.

Keywords: chronic obstructive pulmonary disease; Qingfei-yangyin decoction; non-invasive ventilation; oxygenation function; lung compliance

DOI:10.19296/j.cnki.1008-2409.2024-03-023

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