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CHEN Yanle ^¢Ú , ZHANG Huifeng, BAO Weiping, LIU Kemian, CHU 

Xiaoqiu ^¢Û

(The Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing 210029, China)

Abstract Objective: To observe the clinical efficacy of Shutangluo recipe in the treatment of patients with diabetic peripheral neuropathy (DPN) of phlegm-stasis blocking collateral type. Methods: 60 cases of DPN patients were randomly divided into the observation group and control group, each with 30 cases. The control group were given oral treatment with thioctic acid tablets combined with epalrestat tablets, while the  observation group were given Shutangluo recipe on the basis of the treatment for the control group. Both groups were treated for 8 weeks. The clinical efficacy, TCM syndrome scores, the motor and sensory nerve conduction velocity of the common peroneal nerve and the median nerve before and after treatment were compared between the two groups. Results: The total effective rate of the observation group was 93.33 % , which was higher than 73.33 % of the control group, the difference was statistically significant (P<0.05). After treatment, TCM syndrome scores, the motor and sensory nerve conduction velocity of the common peroneal nerve and the median nerve were improved in both groups, and the improvement in the observation group was more obvious (P<0.05). Conclusion: Shutangluo recipe can significantly improve the clinical efficacy, TCM syndromes and neurological function of DPN patients with phlegm-stasis blocking collateral type, which is worthy of clinical application.

Keywords: Shutangluo recipe; diabetic peripheral neuropathy; clinical efficacy

DOI:10.19296/ j.cnki.1008-2409.2023-01-007

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